Distal bile duct carcinomas and pancreatic ductal adenocarcinomas: postulating a common tumor entity
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چکیده
منابع مشابه
Distal bile duct carcinomas and pancreatic ductal adenocarcinomas: postulating a common tumor entity
The set definition of distal cholangiocarcinomas and adenocarcinomas of the pancreatic head is challenged by their close anatomical relation, similar growth pattern, and corresponding therapeutic outcome. They show a mutual development during embryologic organ formation and share phenotypic characteristics. This review will highlight the similarities with regard to the common origin of their pr...
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BACKGROUND Carcinoid tumors rarely arise in the extrahepatic bile duct and can be difficult to distinguish from carcinoma. There are no reports of clear cell carcinoid (CCC) tumors in the distal bile duct (DBD) to the best of our knowledge. Herein, we report a CCC tumor in the DBD and review the literature concerning extrahepatic bile duct carcinoid tumors. CASE PRESENTATION A 73-old man pres...
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The cell of origin of pancreatic ductal adenocarcinoma (PDAC) has been controversial. Here, we show that identical oncogenic drivers trigger PDAC originating from both ductal and acinar cells with similar histology but with distinct pathophysiology and marker expression dependent on cell of origin. Whereas acinar-derived tumors exhibited low AGR2 expression and were preceded by pancreatic intra...
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A case of primary carcinoid tumor of the common bile duct is presented. Diagnostic and therapeutic uncertainties of this extremely rare cause of jaundice are discussed.
متن کاملMR cholangiopancreatography findings of heterotopic pancreatic tissue in the distal common bile duct.
Heterotopic pancreas is defined as the presence of pancreatic tissue at sites other than the pancreas. Involved sites may be the stomach, duodenum, proximal jejunum, ileum, congenital duodenal web, Meckel's diverticulum, ampulla of Vater, and the main pancreatic duct. We report the magnetic resonance cholangiopancreatography findings of a patient who had biliary obstruction due to heterotopic p...
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ژورنال
عنوان ژورنال: Cancer Medicine
سال: 2015
ISSN: 2045-7634,2045-7634
DOI: 10.1002/cam4.566